Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077028 | 0.80 | NLRP3 (0.55) | NLRP3HSD17B10ALDH1A1MEN1USP2 | |
| SCHEMBL11073152 | 0.78 | HSD17B10 (0.44) | HSD17B10ALDH1A1MEN1USP2GLA | |
| SCHEMBL11079618 | 0.76 | GRIK2 (0.52) | HSD17B10ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11086321 | 0.76 | GRIK2 (0.52) | HSD17B10ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11290683 | 0.76 | GRIK2 (0.47) | NLRP3KMT2ATDP1GRIK2GRIK1 | |
| SCHEMBL11435483 | 0.70 | PTGER4 (0.51) | NLRP3ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11076968 | 0.70 | NLRP3 (0.50) | NLRP3ALDH1A1MEN1KMT2AADORA3 | |
| SCHEMBL11077060 | 0.70 | GRIK2 (0.43) | HSD17B10ALDH1A1TSHRTDP1L3MBTL1 | |
| SCHEMBL11078342 | 0.69 | TLR8 (0.54) | NLRP3HSD17B10ALDH1A1USP2TSHR | |
| SCHEMBL11078753 | 0.68 | TLR8 (0.44) | NLRP3HSD17B10ALDH1A1MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |