Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 12/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079618 | 0.84 | GRIK2 (0.52) | HSD17B10ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11075432 | 0.84 | SHMT2 (0.48) | HSD17B10ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL11290683 | 0.83 | GRIK2 (0.47) | KMT2ATDP1PTGER4KDM4EHPGD | |
| SCHEMBL11077028 | 0.81 | NLRP3 (0.55) | HSD17B10ALDH1A1MEN1USP2TSHR | |
| SCHEMBL11435483 | 0.79 | PTGER4 (0.51) | ALDH1A1MEN1KMT2ATDP1L3MBTL1 | |
| SCHEMBL11075906 | 0.78 | NLRP3 (0.50) | HSD17B10ALDH1A1MEN1USP2GLA | |
| SCHEMBL11441847 | 0.77 | HTR6 (0.42) | HSD17B10ALDH1A1TSHRPTGER4KDM4E | |
| SCHEMBL11448810 | 0.77 | SHMT2 (0.48) | HSD17B10ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11078753 | 0.77 | TLR8 (0.44) | HSD17B10ALDH1A1MEN1USP2TSHR | |
| SCHEMBL11083637 | 0.77 | ALDH1A1 (0.62) | HSD17B10ALDH1A1MEN1KMT2APTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |