Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | VDR | P11473 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079618 | 0.86 | GRIK2 (0.52) | GRIK2POLBNPSR1GRIK1KDM4E | |
| SCHEMBL11182201 | 0.84 | PSEN1 (0.45) | KDM4EKMT2AHPGDMAPTTLR7 | |
| SCHEMBL11073152 | 0.83 | HSD17B10 (0.44) | KDM4ETDP1KMT2AGAAHPGD | |
| SCHEMBL11077028 | 0.83 | NLRP3 (0.55) | NPSR1KDM4EKMT2AHPGDMAPT | |
| SCHEMBL11086321 | 0.79 | GRIK2 (0.52) | GRIK2POLBNPSR1GRIK1KDM4E | |
| SCHEMBL11435483 | 0.76 | PTGER4 (0.51) | NPSR1KDM4ETDP1KMT2AHPGD | |
| SCHEMBL11075906 | 0.76 | NLRP3 (0.50) | GRIK2POLBNPSR1GRIK1KDM4E | |
| SCHEMBL4052208 | 0.75 | GRIK2 (0.48) | GRIK2GRIK1KDM4ETDP1KMT2A | |
| SCHEMBL11079355 | 0.75 | ALDH1A1 (0.55) | NPSR1KDM4EGAAHPGDMAPT | |
| SCHEMBL11078753 | 0.74 | TLR8 (0.44) | GRIK2NPSR1KDM4EKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340607-A | Antimicrobial 3H-naphtho[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |