Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070020 | 0.81 | OPRM1 (0.49) | BCHEOPRM1OPRL1ADAM17KDM1A | |
| SCHEMBL11075825 | 0.81 | OPRM1 (0.51) | BCHEOPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11069896 | 0.79 | OPRM1 (0.43) | BCHEOPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11074113 | 0.79 | OPRM1 (0.42) | OPRM1OPRL1 | |
| SCHEMBL11075002 | 0.77 | HTR1D (0.36) | OPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11073770 | 0.76 | OPRM1 (0.37) | OPRM1MEN1KMT2A | |
| SCHEMBL11077463 | 0.75 | OPRM1 (0.46) | OPRM1OPRL1 | |
| SCHEMBL11079387 | 0.75 | OPRM1 (0.37) | OPRM1MEN1KMT2A | |
| Ethylbenzene SCHEMBL11070027 | 0.74 | OPRM1 (0.51) | BCHEOPRM1OPRL1ADAM17KDM1A | |
| SCHEMBL11076119 | 0.73 | OPRM1 (0.40) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |