Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GRM5 | P41594 | 4/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.47 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11082813 | 0.83 | GFER (0.57) | KDM4EALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL11077598 | 0.82 | ATM (0.51) | KDM4EALDH1A1KMT2AGRM5HSD17B10 | |
| SCHEMBL11076159 | 0.81 | ADRB2 (0.57) | KDM4EALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL11080963 | 0.77 | KMT2A (0.56) | KDM4EALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL22481434 | 0.76 | SLC6A7 (0.53) | KDM4EALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL14411664 | 0.75 | SLC6A7 (0.54) | KDM4EALDH1A1KMT2AHSD17B10HPGD | |
| SCHEMBL11080396 | 0.74 | POLB (0.50) | KDM4EHSD17B10LMNAMAPTHPGD | |
| SCHEMBL11155548 | 0.74 | L3MBTL1 (0.61) | KDM4EALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL11079223 | 0.74 | KDM4E (0.72) | KDM4EALDH1A1KMT2AHSD17B10LMNA | |
| SCHEMBL14224744 | 0.73 | CKS1B (0.53) | KDM4EALDH1A1KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | claimed |
| US-4439606-A | ANTICHOLESTEROL, ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| EP-0094498-A2 | Antiatherosclerotic 1-piperazine derivatives | AMERICAN CYANAMID COMPANY (US) | 1983-11-23 | — | — | EP | disclosed |