Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170695 | 0.80 | ADORA2A (0.41) | AHCYJAK2ADORA2AADORA1PI4KA | |
| 3-Ethyladenine SCHEMBL48200 | 0.77 | ADORA2A (0.50) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL9108201 | 0.75 | ADORA2A (0.36) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| 3-Propyladenine SCHEMBL15756434 | 0.74 | ADORA2A (0.53) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL27962598 | 0.74 | ADORA2A (0.53) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL28115671 | 0.74 | ADORA2A (0.56) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL5513295 | 0.74 | ADORA2A (0.35) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL4541360 | 0.73 | ADORA2A (0.62) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL1020380 | 0.73 | AHCY (1.00) | AHCYADORA2AADORA1PI4KAPI4K2B | |
| SCHEMBL13997084 | 0.72 | ADORA2A (0.43) | AHCYADORA2AADORA1PI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-4430495-A | Process for preparing lincomycin and clindamycin ribonucleotides | THE UPJOHN COMPANY (US) | 1984-02-07 | — | — | US | disclosed |