SCHEMBL27962598

SCHEMBL27962598

Nc1ncn(CCO)c2ncnc1-2

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 7/20 0.53
ADORA1 P30542 4/20 0.53
ADCY1 Q08828 1/20 0.36
ADORA2B P29275 3/20 0.36
AHCY P23526 6/20 0.35
CYP1A2 P05177 1/20 0.33
FGFR1 P11362 1/20 0.33
SLC22A6 Q4U2R8 1/20 0.33
LMNA P02545 1/20 0.33
PI4KA P42356 1/20 0.33
PI4K2B Q8TCG2 1/20 0.33
PI4K2A Q9BTU6 1/20 0.33
PI4KB Q9UBF8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-Propyladenine SCHEMBL15756434 0.83 ADORA2A (0.53) ADORA2AADORA1ADORA2BLMNAPI4KA
SCHEMBL9108201 0.80 ADORA2A (0.36) ADORA2AADORA1ADORA2BAHCYLMNA
SCHEMBL5513295 0.79 ADORA2A (0.35) ADORA2AADORA1ADORA2BAHCYLMNA
3-Ethyladenine SCHEMBL48200 0.79 ADORA2A (0.50) ADORA2AADORA1ADORA2BAHCYLMNA
SCHEMBL31058427 0.76 HSP90B1 (0.38) ADORA2A
SCHEMBL170695 0.75 ADORA2A (0.41) ADORA2AADORA1ADORA2BAHCYPI4KA
SCHEMBL11076308 0.74 AHCY (0.57) ADORA2AADORA1ADORA2BAHCYPI4KA
SCHEMBL13997084 0.73 ADORA2A (0.43) ADORA2AADORA1ADORA2BAHCYPI4KA
SCHEMBL3520240 0.72 SRC (0.38) LMNAPI4KB
3-Benzyladenine SCHEMBL5352368 0.72 ADORA2A (0.56) ADORA2ALMNAPI4KAPI4K2BPI4K2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103852548-B Detecting method for 3-hydroxyethyl adenine (3-HOEtA) in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-06-24 CN claimed
CN-103823009-B Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-02-18 CN claimed
CN-103808836-B Determination method of 3-alkylated adenine DNA adducts in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-01-07 CN claimed
CN-103822988-B Application of LC (liquid chromatogram) tandem mass spectrum method in biological monitoring of N3-(2-hydroxyethyl)-adenine in large-scale smoker crowd samples NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-01-07 CN claimed
CN-103852548-A Detecting method for 3-hydroxyethyl adenine (3-HOEtA) in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-06-11 CN claimed
CN-103823009-A Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN claimed
CN-103822988-A Application of LC (liquid chromatogram) tandem mass spectrum method in biological monitoring of N3-(2-hydroxyethyl)-adenine in large-scale smoker crowd samples NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN claimed
CN-103808836-A Determination method of 3-alkylated adenine DNA adducts in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-21 CN claimed
CN-103852548-B Detecting method for 3-hydroxyethyl adenine (3-HOEtA) in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-06-24 CN disclosed
CN-103852548-B Detecting method for 3-hydroxyethyl adenine (3-HOEtA) in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-06-24 CN disclosed
CN-103852548-B Detecting method for 3-hydroxyethyl adenine (3-HOEtA) in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-06-24 CN disclosed
CN-103823009-B Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-02-18 CN disclosed
CN-103823009-B Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-02-18 CN disclosed
CN-103822988-B Application of LC (liquid chromatogram) tandem mass spectrum method in biological monitoring of N3-(2-hydroxyethyl)-adenine in large-scale smoker crowd samples NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2015-01-07 CN disclosed
CN-103823009-A Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN disclosed
CN-103823009-A Application of liquid chromatography tandem mass spectrogram method in biological monitoring of 3-alkylation adenine in mass smokers NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN disclosed
CN-103822988-A Application of LC (liquid chromatogram) tandem mass spectrum method in biological monitoring of N3-(2-hydroxyethyl)-adenine in large-scale smoker crowd samples NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN disclosed
CN-103822988-A Application of LC (liquid chromatogram) tandem mass spectrum method in biological monitoring of N3-(2-hydroxyethyl)-adenine in large-scale smoker crowd samples NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-28 CN disclosed
CN-103808836-A Determination method of 3-alkylated adenine DNA adducts in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-21 CN disclosed
CN-103808836-A Determination method of 3-alkylated adenine DNA adducts in urine NAT TOBACCO QUALITY SUPERVISION & INSPECTION CT 2014-05-21 CN disclosed