Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079047 | 0.91 | CRHR1 (0.34) | CRHR1 | |
| SCHEMBL11071790 | 0.86 | TSHR (0.36) | CRHR1ALDH1A1TSHR | |
| SCHEMBL11068867 | 0.83 | CRHR1 (0.34) | CRHR1TSHR | |
| SCHEMBL11069371 | 0.83 | TSHR (0.35) | CRHR1ALDH1A1TSHR | |
| SCHEMBL11074056 | 0.80 | CRHR1 (0.33) | CRHR1TSHR | |
| SCHEMBL11072624 | 0.80 | TSHR (0.35) | TSHR | |
| SCHEMBL11072605 | 0.80 | SLC6A4 (0.41) | KCNN4 | |
| SCHEMBL11078545 | 0.80 | KCNN4 (0.33) | CRHR1KCNN4LTC4S | |
| SCHEMBL11071524 | 0.78 | OPRM1 (0.42) | TSHR | |
| SCHEMBL11078728 | 0.77 | TSHR (0.35) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |