Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076565 | 0.90 | KDM4E (0.45) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL9772660 | 0.68 | KDM4E (0.41) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL8812752 | 0.68 | KDM4E (0.44) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL4790892 | 0.68 | KDM4E (0.50) | KDM4ETSHRGPR35KMT2AMEN1 | |
| SCHEMBL9543595 | 0.68 | KDM4E (0.50) | KDM4ETSHRKMT2AMEN1MAPT | |
| SCHEMBL11129579 | 0.68 | TSHR (0.49) | KDM4ETSHRGPR35KMT2AMEN1 | |
| SCHEMBL10657820 | 0.68 | ALDH1A1 (0.49) | TSHRGPR35KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11035929 | 0.66 | GPR35 (0.41) | KDM4ETSHRGPR35MAPTMAPK1 | |
| SCHEMBL11035931 | 0.66 | GPR35 (0.41) | KDM4ETSHRGPR35MAPTMAPK1 | |
| SCHEMBL10797745 | 0.66 | TDP1 (0.44) | KDM4ETSHRGPR35KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960181-B2 | Chromoionophore and method of determining potassium ions | OPTI MEDICAL SYSTEMS (US) | 2011-06-14 | — | — | US | disclosed |
| US-20070259443-A1 | CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS | OPTI MEDICAL SYSTEMS, INC. | 2007-11-08 | — | — | US | disclosed |
| US-6211359-B1 | QUANTITATIVE ANALYSIS | AVL MEDICAL INSTRUMENTS (CH) | 2001-04-03 | — | — | US | disclosed |