Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076676 | 0.76 | HSD11B1 (0.54) | HSD11B1EPHX2 | |
| SCHEMBL21376619 | 0.75 | HSD11B1 (0.47) | HSD11B1ALDH1A1EPHX2 | |
| SCHEMBL14503294 | 0.71 | L3MBTL1 (0.52) | HSD11B1KMT2AEPHX2EPHX1 | |
| SCHEMBL24105897 | 0.70 | HSD11B1 (0.42) | HSD11B1EPHX2 | |
| SCHEMBL27643099 | 0.70 | ALDH1A1 (0.43) | HSD11B1ALDH1A1KMT2AEPHX2 | |
| SCHEMBL9431190 | 0.70 | TDP1 (0.52) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL12994524 | 0.70 | HSD11B1 (0.33) | HSD11B1EPHX2 | |
| SCHEMBL11100497 | 0.69 | HSD11B1 (0.34) | HSD11B1EPHX2EPHX1 | |
| SCHEMBL19909922 | 0.69 | ALDH1A1 (0.39) | ALDH1A1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11181398 | 0.68 | HSD11B1 (0.37) | HSD11B1CA3CA5ACA5BEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6409909-B1 | MULTIDIMENSIONAL SYSTEM FOR THE REAGENT-FREE, CONTINUOUS DETECTION OF A SUBSTANCE; AMPEROMETRY AND OPTICAL SENSORS; | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2002-06-25 | — | — | US | disclosed |