Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.36 |
| ▸ | NAAA | Q02083 | 4/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068338 | 0.94 | ABCB11 (0.38) | ABCB11LMNAMAPTMAPK1GPR119 | |
| SCHEMBL11078717 | 0.94 | ABCB11 (0.38) | ABCB11LMNAMAPTMAPK1GPR119 | |
| SCHEMBL11079388 | 0.92 | EPHX1 (0.41) | GPR119NAAAEPHX1 | |
| SCHEMBL11068963 | 0.89 | SIGMAR1 (0.39) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11075218 | 0.89 | SIGMAR1 (0.39) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11077158 | 0.89 | SIGMAR1 (0.39) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11077066 | 0.89 | CYP4F2 (0.38) | ABCB11LMNAMAPTMAPK1GPR119 | |
| SCHEMBL11074335 | 0.88 | ABCB11 (0.38) | ABCB11LMNAMAPTMAPK1NAAA | |
| SCHEMBL11076593 | 0.87 | SIGMAR1 (0.41) | NAAAEPHX1 | |
| SCHEMBL11075681 | 0.87 | SIGMAR1 (0.41) | NAAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |