Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070123 | 0.81 | GAA (0.46) | TP53MAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL11076847 | 0.81 | CYP3A4 (0.45) | ALDH1A1GAAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL8302857 | 0.68 | OPRM1 (0.47) | ALDH1A1GAASMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL28312922 | 0.68 | MAPT (0.43) | TP53MAPTALDH1A1GAATDP1 | |
| SCHEMBL28704750 | 0.67 | OPRM1 (0.55) | MAPTALDH1A1GAAOPRM1OPRD1 | |
| SCHEMBL6722972 | 0.67 | MMP13 (0.48) | GAASMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL19975419 | 0.67 | CYP3A4 (0.46) | ALDH1A1GAAKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL11082322 | 0.67 | MAPT (0.43) | TP53MAPTALDH1A1GAATDP1 | |
| SCHEMBL15367166 | 0.67 | METAP2 (0.57) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL15374437 | 0.67 | METAP2 (0.57) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432901-A | CHEMICAL INTERMEDIATE FOR PENICIULINS, THIENAMYCINS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-02-21 | — | — | US | disclosed |