SCHEMBL11077079

SCHEMBL11077079

CCc1ccccc1OP(O)(=S)Cl

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.43
MAPT P10636 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TSHR P16473 1/20 0.39
HSD17B10 Q99714 1/20 0.39
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
SRC P12931 1/20 0.36
CXCL8 P10145 1/20 0.36
KDM4E B2RXH2 2/20 0.36
NISCH Q9Y2I1 1/20 0.35
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5852168 0.84 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL5552769 0.82 L3MBTL1 (0.43) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL1591871 0.81 L3MBTL1 (0.48) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL31741554 0.79 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL11509880 0.79 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL29647909 0.79 INPPL1 (0.53) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL5852162 0.79 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL2150397 0.79 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL1101447 0.79 INPPL1 (0.53) L3MBTL1MAPTNPSR1TSHRHSD17B10
SCHEMBL778837 0.78 SMN1; SMN2 (0.49) L3MBTL1MAPTNPSR1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0065039-B1 AN O-(N-ALKOXY-PYRIDINECARBOXIMIDOYL)PHOSPHATE, A PROCESS FOR PRODUCING THE SAME, AND AN INSECTICIDAL OR ACARICIDAL COMPOSITION CONTAINING THE SAME ISHIHARA SANGYO KAISHA LTD. (JP) 1984-08-22 EP disclosed
EP-0065039-A1 An O-(N-alkoxy-pyridinecarboximidoyl)phosphate, a process for producing the same, and an insecticidal or acaricidal composition containing the same ISHIHARA SANGYO KAISHA LTD. (JP) 1982-11-24 EP disclosed
US-4327089-A O-(N-Alkoxy-pyridinecarboximidoyl) phosphates, process for producing the same, and insecticidal or acaridical compositions containing the same ISHIHARA SANGYO KAISHA LTD. (JP) 1982-04-27 US disclosed