SCHEMBL5852168

SCHEMBL5852168

CCc1ccccc1OP(=O)(O)Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HSD17B10 Q99714 2/20 0.40
TSHR P16473 1/20 0.40
HPGD P15428 2/20 0.39
ATM Q13315 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
LMNA P02545 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
HTT P42858 1/20 0.38
INPPL1 O15357 1/20 0.37
INPP5B P32019 1/20 0.37
INPP5A Q14642 1/20 0.37
ALDH1A1 P00352 3/20 0.37
KDM4E B2RXH2 2/20 0.37
GAA P10253 1/20 0.37
SRC P12931 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1101447 0.85 INPPL1 (0.53) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL31741554 0.85 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL2150397 0.85 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL29647909 0.85 INPPL1 (0.53) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL5852162 0.85 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL11509880 0.85 L3MBTL1 (0.47) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL11077079 0.84 L3MBTL1 (0.43) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL778837 0.83 SMN1; SMN2 (0.49) L3MBTL1MAPTNPSR1HSD17B10TSHR
SCHEMBL9796117 0.82 THRA (0.53)
SCHEMBL5852177 0.82 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1HSD17B10TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3831388-A1 CYCLOPENTENYL PURINE DERIVATIVE OR SALT THEREOF FUJIFILM Corporation (JP) 2021-06-09 EP disclosed
US-7153901-B2 Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production ALBEMARLE CORPORATION (US) 2006-12-26 US disclosed
EP-1685176-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2006-08-02 EP disclosed
WO-2005052018-A2 FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES ALBEMARLE CORPORATION (US) 2005-06-09 WO disclosed
US-20050113495-A1 Flame retardant, additive compositions, and flame retardant polyurethanes ALBEMARLE CORPORATION 2005-05-26 US disclosed
US-4822779-A INSECTICIDES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1989-04-18 US disclosed