Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 6/20 | 0.59 |
| ▸ | BCL2 | P10415 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAOA | P21397 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782111 | 0.92 | MCL1 (0.70) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL11861191 | 0.79 | MCL1 (0.53) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL11077084 | 0.79 | MAPT (0.65) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL11077569 | 0.79 | MCL1 (0.58) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL11077111 | 0.78 | HSP90AA1 (0.55) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL22233094 | 0.77 | S100A4 (0.55) | MEN1KMT2AMAOAMAPTMAPK1 | |
| SCHEMBL5999520 | 0.77 | MAPT (0.55) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL7918785 | 0.76 | MEN1 (0.70) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL30829230 | 0.76 | MEN1 (0.70) | MCL1BCL2MEN1KMT2AMAOA | |
| SCHEMBL1039833 | 0.75 | MAOA (0.78) | MCL1BCL2MEN1KMT2AMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447420-A | Fluorenone esters of phosphoric and phosphonic acids as insecticides | VELSICOL CHEMICAL CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |