Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077184 | 1.00 | MAPT (0.49) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL8408988 | 0.92 | MAPT (0.53) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL153153 | 0.88 | ALDH1A1 (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11011084 | 0.87 | CYP1A2 (0.56) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10745247 | 0.85 | LMNA (0.51) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10745243 | 0.85 | LMNA (0.51) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL12328528 | 0.83 | SMN1; SMN2 (0.53) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL31212587 | 0.78 | KMT2A (0.46) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11250495 | 0.78 | LMNA (0.49) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10831403 | 0.78 | ALDH1A1 (0.47) | MAPTALDH1A1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007633-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |