Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658582 | 0.83 | CES2 (0.49) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL8532004 | 0.83 | CES2 (0.49) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL8532009 | 0.83 | CES2 (0.49) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL8408988 | 0.82 | MAPT (0.53) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL12328528 | 0.82 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL11100077 | 0.79 | LMNA (0.38) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL153153 | 0.78 | ALDH1A1 (0.56) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL11077182 | 0.78 | MAPT (0.49) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL11077184 | 0.78 | MAPT (0.49) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 | |
| SCHEMBL30956918 | 0.78 | SMN1; SMN2 (0.56) | LMNASMN1; SMN2KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4347342-A | Process for initiating radical reactions employing hydroximic acid derivatives | AKZONA INCORPORATED (US) | 1982-08-31 | — | — | US | disclosed |