Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.32 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1547141 | 0.89 | RXRA (0.40) | ALOX5PTGS2HSP90AA1TP53LMNA | |
| SCHEMBL712969 | 0.83 | NPC1 (0.38) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL29706577 | 0.83 | NPC1 (0.38) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL11277905 | 0.83 | ALOX5 (0.33) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL29349567 | 0.83 | NPC1 (0.41) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL29241 | 0.83 | NPC1 (0.41) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL22080465 | 0.82 | NPC1 (0.37) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL13700658 | 0.82 | MEN1 (0.34) | ALOX5PTGS2RAB9AMEN1KMT2A | |
| SCHEMBL24236671 | 0.81 | NPC1 (0.36) | ALOX5PTGS2NPC1RAB9AHSP90AA1 | |
| SCHEMBL24236672 | 0.81 | NPC1 (0.36) | ALOX5PTGS2NPC1RAB9AHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481315-A | LACQUERS | CIBA-GEIGY CORPORATION (US) | 1984-11-06 | — | — | US | disclosed |
| US-4289686-A | FOR LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-09-15 | — | — | US | disclosed |