Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.31 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.31 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10447442 | 0.90 | ALOX5 (0.35) | ALOX5PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24205703 | 0.85 | CA1 (0.42) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL11077606 | 0.83 | ALOX5 (0.37) | ALOX5PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29706577 | 0.81 | NPC1 (0.38) | ALOX5PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL712969 | 0.81 | NPC1 (0.38) | ALOX5PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL21800990 | 0.81 | CYP3A4 (0.38) | ALOX5PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL29241 | 0.80 | NPC1 (0.41) | ALOX5PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL29349567 | 0.80 | NPC1 (0.41) | ALOX5PTGS2NPC1RAB9AMEN1 | |
| SCHEMBL22080465 | 0.80 | NPC1 (0.37) | ALOX5PTGS2NPC1RAB9AALDH1A1 | |
| SCHEMBL1547141 | 0.79 | RXRA (0.40) | ALOX5PTGS2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010516-B1 | POLYALKYLPIPERIDINE DERIVATIVES, THEIR APPLICATION AS LIGHT STABILISERS AND POLYMERS STABILISED THEREWITH | CIBA-GEIGY AG (CH) | 1982-07-14 | — | — | EP | disclosed |
| EP-0010516-A1 | Polyalkylpiperidine derivatives, their application as light stabilisers and polymers stabilised therewith | CIBA-GEIGY AG (CH) | 1980-04-30 | — | — | EP | disclosed |