Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | PGK1 | P00558 | 6/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.35 |
| ▸ | RHEB | Q15382 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11207413 | 0.79 | IGFBP5 (0.32) | — | |
| SCHEMBL7105783 | 0.74 | FABP7 (0.47) | LMNAFABP7FABP3FABP5TDP1 | |
| 2,3-Dihydroxy-6,7-Dichloroquinoxaline SCHEMBL1259521 | 0.73 | MMP1 (0.50) | MMP1MMP2MMP3PGK1NQO2 | |
| SCHEMBL6108802 | 0.72 | ALDH1A1 (0.44) | MMP1MMP2MMP3GRIN2DGRIN3B | |
| SCHEMBL11084120 | 0.69 | ALDH1A1 (0.39) | LMNANQO2TDP1 | |
| SCHEMBL4649774 | 0.68 | NPC1 (0.53) | LMNAFABP7FABP3FABP5 | |
| 6,7-Dichloro-3-Hydroxy-2-Quinoxalinecarboxylic Acid SCHEMBL4287210 | 0.68 | GRIN2D (0.53) | MMP1MMP2MMP3RHEBGRIN2D | |
| SCHEMBL6227029 | 0.67 | PARP1 (0.48) | — | |
| SCHEMBL5693517 | 0.67 | TSHR (0.42) | LMNAFABP7FABP3FABP5TDP1 | |
| SCHEMBL11194302 | 0.67 | MAPT (0.45) | LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050790-B1 | PREPARATION OF ALPHA-CHLORINATED NITROGEN HETEROCYCLES | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |