Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGFBP5 | P24593 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077641 | 0.79 | MMP1 (0.35) | — | |
| SCHEMBL6110713 | 0.76 | L3MBTL1 (0.45) | IGFBP5MEN1POLBMAPTKMT2A | |
| SCHEMBL1552379 | 0.74 | KDM4E (0.35) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL10348834 | 0.73 | MAPT (0.52) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL11228991 | 0.72 | IDO1 (0.50) | MEN1USP2POLBMAPTKMT2A | |
| SCHEMBL11219518 | 0.71 | MAPT (0.46) | MEN1NPC1USP2POLBMAPT | |
| Hydrochloric Acid SCHEMBL9797561 | 0.71 | MAPT (0.50) | MEN1NPC1USP2POLBMAPT | |
| SCHEMBL11084120 | 0.69 | ALDH1A1 (0.39) | MEN1NPC1POLBMAPTKMT2A | |
| SCHEMBL11333482 | 0.68 | — | — | |
| SCHEMBL6107090 | 0.67 | KDM4E (0.54) | MAPTKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0010722-B1 | MONOAZO-COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-04-20 | — | — | EP | disclosed |
| EP-0010722-A1 | Monoazo-compounds, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-05-14 | — | — | EP | disclosed |