SCHEMBL1743791

SCHEMBL1743791

CC(O)CCC(=O)OCCC(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.42
ADRA1A P35348 1/20 0.42
MAPT P10636 2/20 0.41
BLM P54132 1/20 0.41
ALDH1A1 P00352 1/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRA1 P14867 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRG2 P18507 2/20 0.39
GABRB3 P28472 2/20 0.39
GABRA5 P31644 2/20 0.39
GABRA3 P34903 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39
GABRE P78334 2/20 0.39
GABRA6 Q16445 2/20 0.39
GABRG1 Q8N1C3 2/20 0.39
GABRG3 Q99928 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5898576 0.89 MAPT (0.40) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL14494720 0.86 CA1 (0.41) ADRA2AADRA1AMAPTBLMGABRP
SCHEMBL11077835 0.84 ADRA2A (0.47) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL310867 0.82 MAPT (0.47) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL1271226 0.82 ADRA2A (0.39) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL30173728 0.82 ADRA2A (0.43) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL821822 0.82 ADRA2A (0.43) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL1258235 0.81 MAPT (0.47) ADRA2AADRA1AMAPTALDH1A1DGKA
SCHEMBL8611593 0.81 ADRA2A (0.44) ADRA2AADRA1AMAPTBLMALDH1A1
SCHEMBL11548670 0.80 GABRP (0.43) ADRA2AADRA1AMAPTBLMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2387956-B1 Anchoring device COVIDIEN LP (US) 2019-03-13 EP disclosed
EP-2387955-B1 Anchoring device COVIDIEN LP (US) 2013-11-13 EP disclosed
EP-2491871-A1 Anchoring device Tyco Healthcare Group LP (US) 2012-08-29 EP disclosed
EP-2387955-A1 Anchoring device Tyco Healthcare Group LP (US) 2011-11-23 EP disclosed
EP-2387956-A1 Anchoring device Tyco Healthcare Group LP (US) 2011-11-23 EP disclosed
US-20110254393-A1 ELECTRIC MOTOR DEVICE DENSO CORPORATION (JP) 2011-10-20 US disclosed
US-20110253559-A1 Hat storing container MCDONALD LAMARCUS 2011-10-20 US disclosed