Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11764927 | 0.90 | RAB9A (0.52) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL11077918 | 0.89 | RAB9A (0.49) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11764061 | 0.84 | KDM4E (0.50) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11399779 | 0.83 | RAB9A (0.44) | MEN1KMT2AMAPTLMNAHTT | |
| Pirazolac SCHEMBL153631 | 0.83 | KDM4E (0.51) | MEN1KMT2AHTTCA12CA1 | |
| Pirazolac SCHEMBL10952997 | 0.82 | KDM4E (0.50) | MEN1KMT2AHTTCA12CA1 | |
| SCHEMBL11469421 | 0.82 | MAPT (0.43) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL11764727 | 0.81 | RAB9A (0.64) | MEN1KMT2AHTTPTGS2RAB9A | |
| SCHEMBL11076213 | 0.78 | PPP1CA (0.49) | MEN1KMT2AMAPTHTTPTGS2 | |
| SCHEMBL11443525 | 0.76 | KDM4E (0.56) | KMT2AMAPTLMNACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022906-B1 | PROCESS FOR THE PREPARATION OF PYRAZOLE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0022906-A1 | Process for the preparation of pyrazole derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-01-28 | — | — | EP | disclosed |