SCHEMBL1107831

SCHEMBL1107831

Fc1cc(Cl)cc(CC(NC2=NCCS2)c2cccc(Cl)c2Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.41
ATM Q13315 1/20 0.39
HPGD P15428 1/20 0.39
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
ALDH1A1 P00352 3/20 0.36
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
TP53 P04637 1/20 0.35
POLB P06746 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1107847 0.93 ATM (0.43) MAPTATMHPGDMEN1KMT2A
SCHEMBL1096470 0.84 ATM (0.41) MAPTATMMEN1KMT2ALMNA
SCHEMBL1107830 0.84 ATM (0.39) MAPTATMHPGDMEN1KMT2A
SCHEMBL14000969 0.83 ATM (0.41) MAPTATMHPGDMEN1KMT2A
SCHEMBL14000960 0.82 ATM (0.43) MAPTATMHPGDMEN1KMT2A
SCHEMBL14000967 0.80 ATM (0.40) MAPTATMHPGDMEN1KMT2A
SCHEMBL14000958 0.79 ATM (0.41) MAPTATMMEN1KMT2ALMNA
SCHEMBL1107826 0.78 ALDH1A1 (0.40) MAPTATMHPGDMEN1KMT2A
SCHEMBL3415134 0.78 MAPT (0.44) MAPTATMHPGDMEN1KMT2A
SCHEMBL14000948 0.77 ATM (0.42) MAPTATMHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153560-B2 Pesticidal active mixtures comprising aminothiazoline compounds BASF SE (DE) 2012-04-10 US disclosed
US-8153560-B2 Pesticidal active mixtures comprising aminothiazoline compounds BASF SE (DE) 2012-04-10 US disclosed
US-20100056469-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2010-03-04 US disclosed
US-20100056469-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2010-03-04 US disclosed
WO-2008104503-A1 PESTICIDAL ACTIVE MIXTURES COMPRISING AMINOTHIAZOLINE COMPOUNDS BASF SE (DE) 2008-09-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056469-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds ACHE, PTMS, CHRM3 MAPT 2950/4885ATM 917/4885HPGD 4354/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.