Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075481 | 0.85 | OPRM1 (0.38) | OPRM1OPRL1OPRK1SLC6A4 | |
| SCHEMBL11071938 | 0.82 | OPRK1 (0.40) | OPRM1OPRL1OPRK1SLC6A4 | |
| SCHEMBL11071524 | 0.80 | OPRM1 (0.42) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL11066779 | 0.80 | TSHR (0.36) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL11066917 | 0.80 | HTT (0.36) | OPRM1OPRL1SLC6A4 | |
| SCHEMBL11079248 | 0.80 | SLC6A4 (0.36) | SLC6A4 | |
| SCHEMBL11069869 | 0.79 | OPRM1 (0.36) | OPRM1OPRL1OPRK1SLC6A4 | |
| SCHEMBL11075825 | 0.79 | OPRM1 (0.51) | OPRM1OPRL1MAOBADAM17BCHE | |
| SCHEMBL11078728 | 0.78 | TSHR (0.35) | OPRM1OPRL1OPRK1SLC6A4 | |
| SCHEMBL11076803 | 0.77 | OPRM1 (0.35) | OPRM1OPRL1OPRK1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |