Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.74 |
| ▸ | NPC1 | O15118 | 9/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.58 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11087870 | 0.84 | KCNK3 (0.81) | RAB9ANPC1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL1452104 | 0.84 | RAB9A (0.71) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL3461653 | 0.83 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL12010995 | 0.82 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL259290 | 0.82 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL10940026 | 0.81 | KCNK3 (0.81) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL2105310 | 0.80 | KCNK3 (0.78) | RAB9ANPC1SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2228108 | 0.79 | RAB9A (0.65) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL27701359 | 0.78 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2HPGDMAPT | |
| SCHEMBL11083807 | 0.78 | KCNK3 (0.82) | RAB9ASMN1; SMN2POLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439444-A | HISTAMINE RECEPTOR ANTAGONISTS | SANOFI (FR) | 1984-03-27 | — | — | US | disclosed |