Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11078736 | 0.78 | RAB9A (0.74) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL259290 | 0.77 | RAB9A (0.69) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL5340030 | 0.73 | MEN1 (0.89) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL24931106 | 0.72 | KDM4E (0.68) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL27701331 | 0.72 | MCL1 (0.57) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL12010995 | 0.71 | RAB9A (0.64) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL27681897 | 0.71 | HDAC3 (0.78) | ALDH1A1HTTSMN1; SMN2TSHRMAPT | |
| SCHEMBL27701329 | 0.71 | SMN1; SMN2 (0.55) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL3461653 | 0.71 | RAB9A (0.63) | RAB9AALDH1A1HTTNPC1SMN1; SMN2 | |
| SCHEMBL13210583 | 0.70 | ALDH1A1 (0.79) | RAB9AALDH1A1NPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101087601-A | Compounds for inhibiting copper-containing amine oxidases and uses thereof | GENMEDICA THERAPEUTICS SL (ES) | 2007-12-12 | — | — | CN | disclosed |