Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11495620 | 0.88 | TLR7 (0.43) | TLR7HDAC1HDAC8HDAC6ATM | |
| SCHEMBL11495618 | 0.83 | TLR7 (0.43) | TLR7HDAC1HDAC8HDAC6ATM | |
| SCHEMBL11075495 | 0.82 | TLR7 (0.50) | TLR7HDAC1HDAC8HDAC6ATM | |
| SCHEMBL9611690 | 0.78 | TLR7 (0.61) | TLR7HDAC1HDAC8HDAC6ATM | |
| SCHEMBL11076059 | 0.77 | TLR7 (0.48) | TLR7ATMKDM4EHSD17B10HPGD | |
| SCHEMBL11079289 | 0.75 | TLR7 (0.51) | TLR7HDAC1HDAC8HDAC6ATM | |
| SCHEMBL11078229 | 0.72 | PARP1 (0.47) | TLR7ATMKDM4EHSD17B10ADORA2A | |
| SCHEMBL11440934 | 0.70 | TLR7 (0.49) | TLR7ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL11449199 | 0.70 | TLR7 (0.46) | TLR7KDM4EADORA2AADORA2BADORA3 | |
| SCHEMBL11495625 | 0.70 | MEN1 (0.39) | TLR7DRD2KDM4EHSD17B10ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |