Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 2/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11076799 | 0.88 | CASR (0.50) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11079618 | 0.88 | GRIK2 (0.52) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11076876 | 0.88 | TLR8 (0.62) | ALDH1A1KDM4ETSHRTLR8CASR | |
| SCHEMBL11026052 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11089329 | 0.81 | KDM4E (0.65) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11074861 | 0.81 | TLR7 (0.52) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11073129 | 0.81 | PARP1 (0.55) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL28288759 | 0.81 | TLR8 (0.51) | ALDH1A1KDM4ETSHRTLR8CASR | |
| SCHEMBL11078342 | 0.80 | TLR8 (0.54) | ALDH1A1KDM4EGAATSHRLMNA | |
| SCHEMBL11078944 | 0.78 | MAPK9 (0.50) | ALDH1A1KDM4EGAATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435417-A | ANTIINFLAMMATORY AGENTS | GRUPPO LEPETIT S.P.A. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0012866-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, PROCESSES FOR PREPARING THEM, COMPOUNDS FOR USE AS ANTIINFLAMMATORY AND ANTIMICROBIAL AGENTS AND COMPOSITIONS FOR THAT USE CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1983-01-19 | — | — | EP | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |