Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079355 | 0.87 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11079618 | 0.86 | GRIK2 (0.52) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11074861 | 0.82 | TLR7 (0.52) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11089329 | 0.82 | KDM4E (0.65) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11073129 | 0.82 | PARP1 (0.55) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11078944 | 0.79 | MAPK9 (0.50) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| Tomoxiprole SCHEMBL525023 | 0.77 | MAPK9 (0.50) | ALDH1A1KDM4ELMNANPSR1SMN1; SMN2 | |
| SCHEMBL11024220 | 0.77 | MAPK9 (0.50) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11085482 | 0.76 | MAPK9 (0.47) | ALDH1A1KDM4ELMNATSHRNPSR1 | |
| SCHEMBL11078342 | 0.76 | TLR8 (0.54) | ALDH1A1KDM4ELMNATSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041630-B1 | NEW 3H-NAPHTHO(1,2-D)IMIDAZOLES, THE PROCESS FOR PREPARING THEM, THE COMPOUNDS FOR USE AS ANTIINFLAMMATORY AGENTS AND COMPOSITIONS CONTAINING THEM | GRUPPO LEPETIT S.P.A. (IT) | 1985-03-13 | — | — | EP | disclosed |
| US-4411907-A | ANALGESICS, ANTIPYRETICS | GRUPPO LEPETIT, S.P.A. (IT) | 1983-10-25 | — | — | US | disclosed |