Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307068 | 0.87 | SLC6A4 (0.38) | TSHR | |
| SCHEMBL10834009 | 0.84 | LTA4H (0.44) | MEN1KMT2APPARGPPARATSHR | |
| SCHEMBL28792157 | 0.82 | ALDH1A1 (0.40) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL8507010 | 0.79 | NPC1 (0.38) | MEN1KMT2AHPGDCNR2 | |
| SCHEMBL11082053 | 0.77 | L3MBTL1 (0.40) | KMT2AHTR1AHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11085629 | 0.75 | SLC6A2 (0.46) | MEN1KMT2ASMN1; SMN2HPGDLMNA | |
| SCHEMBL28468103 | 0.75 | SRD5A2 (0.53) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL16406605 | 0.75 | NPSR1 (0.45) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL16382776 | 0.73 | NPSR1 (0.47) | NPSR1MEN1KMT2APPARGPPARA | |
| SCHEMBL257849 | 0.73 | FFAR1 (0.54) | NPSR1MEN1KMT2APPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467102-A | RACEMIC MODIFICATION WITH BRUCINE | UBE INDUSTRIES, LTD. (JP) | 1984-08-21 | — | — | US | disclosed |