Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DBH | P09172 | 14/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10621224 | 0.81 | DBH (1.00) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10433798 | 0.78 | DBH (0.64) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL10621217 | 0.78 | DBH (0.66) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL4101771 | 0.77 | DBH (0.62) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL9371273 | 0.75 | DBH (0.60) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL6714636 | 0.74 | DBH (1.00) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL7828943 | 0.74 | ALDH1A1 (0.59) | DBHALDH1A1POLBHPGDKMT2A | |
| SCHEMBL2284397 | 0.73 | DBH (0.57) | DBHALDH1A1CYP3A4HPGDKMT2A | |
| SCHEMBL9369333 | 0.72 | DBH (0.56) | DBHALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL9375216 | 0.72 | DBH (0.56) | DBHALDH1A1POLBCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4431815-A | CARDIOTONIC AND ANTISHOCK AGENTS; ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1984-02-14 | — | — | US | disclosed |