Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 5/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.52 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPRA | P18433 | 1/20 | 0.45 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL146561 | 0.93 | CA2 (0.58) | CA1CA2KEAP1IL1RNERAP1 | |
| Benzene SCHEMBL6746153 | 0.93 | CA2 (0.58) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL29756025 | 0.91 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL28176614 | 0.91 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| Hydrochloric Acid SCHEMBL5069950 | 0.91 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| Methane SCHEMBL3339448 | 0.91 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| SCHEMBL3213812 | 0.91 | CA2 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| Ammonia Solution, Strong SCHEMBL4592850 | 0.91 | KEAP1 (0.56) | CA1CA2KEAP1IL1RNERAP1 | |
| Formaldehyde SCHEMBL28212330 | 0.88 | CA2 (0.54) | CA1CA2KEAP1IL1RNERAP1 | |
| Aniline SCHEMBL9191109 | 0.87 | KMT2A (0.58) | CA1CA2KEAP1IL1RNERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486603-A | Preparation of trans cyclohexane 1,4-diamine | AKZONA INCORPORATED (US) | 1984-12-04 | — | — | US | disclosed |
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | disclosed |
| US-4275223-A | Preparation of trans-cyclohexane-1,4-diurethanes | AKZONA INCORPORATED (US) | 1981-06-23 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |