Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL4592850

N.O=S(=O)(O)Nc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
ACP1 P24666 3/20 0.55
IL1RN P18510 1/20 0.54
ERAP1 Q9NZ08 1/20 0.54
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 1/20 0.50
PKM P14618 1/20 0.50
PTPRB P23467 5/20 0.47
PTPN2 P17706 2/20 0.47
PTPN1 P18031 2/20 0.47
PTPRA P18433 1/20 0.47
PGR P06401 1/20 0.46
CA12 O43570 2/20 0.45
CA9 Q16790 2/20 0.45
TSHR P16473 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TMPRSS6 Q8IU80 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL6746153 0.97 CA2 (0.58) KEAP1CA1CA2ACP1IL1RN
SCHEMBL146561 0.97 CA2 (0.58) KEAP1CA1CA2ACP1IL1RN
SCHEMBL28176614 0.95 CA2 (0.56) KEAP1CA1CA2ACP1IL1RN
Hydrochloric Acid SCHEMBL5069950 0.95 CA2 (0.56) KEAP1CA1CA2ACP1IL1RN
Methane SCHEMBL3339448 0.95 CA2 (0.56) KEAP1CA1CA2ACP1IL1RN
SCHEMBL3213812 0.95 CA2 (0.56) KEAP1CA1CA2ACP1IL1RN
SCHEMBL29756025 0.95 CA2 (0.56) KEAP1CA1CA2ACP1IL1RN
Formaldehyde SCHEMBL28212330 0.93 CA2 (0.54) KEAP1CA1CA2ACP1IL1RN
Sulfamate SCHEMBL11079904 0.91 CA1 (0.64) KEAP1CA1CA2ACP1IL1RN
Chloromethane SCHEMBL11386742 0.91 KEAP1 (0.58) KEAP1CA1CA2ACP1IL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919440-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER The Procter and Gamble Company (US) 2008-05-14 EP claimed
EP-1919439-A2 PROCESS FOR BLEACHING KERATIN FIBERS The Procter and Gamble Company (US) 2008-05-14 EP claimed
US-20070231283-A1 Process for bleaching keratin fibers PROCTER & GAMBLE COMPANY, THE 2007-10-04 US claimed
US-20070067925-A1 Agent for simultaneously lightening and coloring of fibers PROCTER & GAMBLE COMPANY, THE 2007-03-29 US claimed
WO-2007026327-A2 PROCESS FOR BLEACHING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
WO-2007026328-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO claimed
EP-1759685-A1 Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster Wella Aktiengesellschaft (DE) 2007-03-07 EP claimed
EP-1759684-A1 Process for bleaching keratin fibers Wella Aktiengesellschaft (DE) 2007-03-07 EP claimed
CN-109771421-A The method for treating vascular leak syndrome 爱尔皮奥治疗有限公司 2019-05-21 CN disclosed
CN-108635350-A The method for treating vascular leak syndrome 爱尔皮奥治疗有限公司 2018-10-12 CN disclosed
CN-105412094-A Compounds, Compositions, And Methods For Preventing Metastasis Of Cancer Cells AKEBIA THERAPEUTICS INC 2016-03-23 CN disclosed
CN-105307498-A Compositions, formulations and methods for treating ocular diseases AERPIO THERAPEUTICS INC 2016-02-03 CN disclosed
EP-1919440-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER The Procter and Gamble Company (US) 2008-05-14 EP disclosed
EP-1919439-A2 PROCESS FOR BLEACHING KERATIN FIBERS The Procter and Gamble Company (US) 2008-05-14 EP disclosed
US-20070231283-A1 Process for bleaching keratin fibers PROCTER & GAMBLE COMPANY, THE 2007-10-04 US disclosed
US-20070067925-A1 Agent for simultaneously lightening and coloring of fibers PROCTER & GAMBLE COMPANY, THE 2007-03-29 US disclosed
WO-2007026328-A2 AGENT FOR SIMULTANEOUS LIGHTENING AND COLORING OF KERATIN FIBRES CONTAINING A SULFAMATE BLEACH BOOSTER THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
WO-2007026327-A2 PROCESS FOR BLEACHING KERATIN FIBERS THE PROCTER & GAMBLE COMPANY (US) 2007-03-08 WO disclosed
EP-1759685-A1 Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster Wella Aktiengesellschaft (DE) 2007-03-07 EP disclosed
EP-1759684-A1 Process for bleaching keratin fibers Wella Aktiengesellschaft (DE) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070067925-A1 Agent for simultaneously lightening and coloring of fibers KIT, KRT18, H1-5 KEAP1 307/4885CA1 434/4885CA2 132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.