Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074581 | 0.85 | CHRM1 (0.37) | CHRM1CHRM3CHRM2CHRM4LMNA | |
| SCHEMBL11073787 | 0.82 | AOC3 (0.44) | CHRM1CHRM3CHRM2AOC3CHRM4 | |
| SCHEMBL2993639 | 0.79 | PIN1 (0.50) | CHRM1CHRM3CHRM2AOC3LMNA | |
| SCHEMBL11507341 | 0.78 | NPC1 (0.56) | LMNAL3MBTL1ALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL10905859 | 0.73 | KCNN4 (0.50) | AOC3LMNACYP1A2CYP2D6L3MBTL1 | |
| SCHEMBL2962351 | 0.71 | ADRB2 (0.37) | L3MBTL1 | |
| SCHEMBL9683893 | 0.69 | AOC3 (0.57) | AOC3LMNACYP2D6L3MBTL1ATM | |
| SCHEMBL60356 | 0.69 | AOC3 (0.57) | AOC3LMNACYP2D6L3MBTL1ATM | |
| SCHEMBL10784988 | 0.68 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL14632149 | 0.67 | AOC3 (0.55) | AOC3LMNACYP2D6L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448980-A | BY CARBONYLATION WITH BIFLUORIDE CATALYSTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-15 | — | — | US | disclosed |