Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.78 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.78 |
| ▸ | EDNRA | P25101 | 1/20 | 0.78 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.78 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11085282 | 0.94 | LMNA (0.72) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL11153426 | 0.90 | LMNA (0.82) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL10028900 | 0.89 | LMNA (0.81) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL4904141 | 0.88 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| SCHEMBL8044673 | 0.88 | LMNA (0.79) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL2635855 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL33963 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL29384458 | 0.88 | LMNA (1.00) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL11289413 | 0.87 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA | |
| Enoxacin SCHEMBL28451325 | 0.87 | LMNA (0.98) | LMNACYP2C9ATP6V1B2TBXA2REDNRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477449-A | DERIVATIVES OF 3-CARBOXY, 4-OXO, 7-/3-THIAZOLIDINYL OR 4-THIAZINYL-1,4-DIHYDRO-1,8-NAPHTHYRINE | WARNER-LAMBERT COMPANY (US) | 1984-10-16 | — | — | US | claimed |
| US-4477449-A | DERIVATIVES OF 3-CARBOXY, 4-OXO, 7-/3-THIAZOLIDINYL OR 4-THIAZINYL-1,4-DIHYDRO-1,8-NAPHTHYRINE | WARNER-LAMBERT COMPANY (US) | 1984-10-16 | — | — | US | disclosed |