Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.31 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CHUK | O15111 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | PRKX | P51817 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1227336 | 1.00 | ROCK2 (0.43) | ROCK2ROCK1LMNATDP1ALOX5 | |
| SCHEMBL8072275 | 1.00 | ROCK2 (0.43) | ROCK2ROCK1LMNATDP1ALOX5 | |
| SCHEMBL10885253 | 0.86 | ROCK2 (0.38) | ROCK2ROCK1LMNATDP1ALOX5 | |
| SCHEMBL2617044 | 0.81 | MAPT (0.38) | LMNATDP1TSHRHTTTHPO | |
| SCHEMBL13165512 | 0.81 | MAPT (0.38) | LMNATDP1TSHRHTTTHPO | |
| SCHEMBL76462 | 0.81 | — | — | |
| SCHEMBL13165462 | 0.81 | MAPT (0.38) | LMNATDP1TSHRHTTTHPO | |
| SCHEMBL6543370 | 0.80 | ROCK2 (0.43) | ROCK2ROCK1LMNATDP1ALOX5 | |
| SCHEMBL22675415 | 0.80 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL10270877 | 0.80 | ROCK2 (0.43) | ROCK2ROCK1LMNATDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452813-A | BENZENESULFONYLOXY-CYCLOHEXYLALKANONES | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-06-05 | — | — | US | disclosed |