SCHEMBL1108052

SCHEMBL1108052

C(#Cc1ccc(-[n+]2ccc(-c3ccncc3)cc2)cc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOTUM Q6P988 1/20 0.45
▸ APP P05067 1/20 0.40
▸ GRM5 P41594 5/20 0.39
▸ PABPC1 P11940 1/20 0.39
▸ APOBEC3A P31941 1/20 0.39
▸ EIF4H Q15056 1/20 0.39
▸ APOBEC3G Q9HC16 1/20 0.39
▸ MAPT P10636 3/20 0.37
▸ LMNA P02545 1/20 0.37
▸ KCNH2 Q12809 1/20 0.37
▸ MEN1 O00255 1/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ KEAP1 Q14145 1/20 0.36
▸ NFE2L2 Q16236 1/20 0.36
▸ CYP1A1 P04798 1/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP1B1 Q16678 1/20 0.35
▸ XIAP P98170 1/20 0.35
▸ BIRC2 Q13490 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14528749 0.84 NOTUM (0.60) NOTUMPABPC1APOBEC3AEIF4HAPOBEC3G
SCHEMBL12216701 0.84 NOTUM (0.58) NOTUMPABPC1APOBEC3AEIF4HAPOBEC3G
Hydrochloric Acid SCHEMBL26599422 0.82 NOTUM (0.56) NOTUMPABPC1APOBEC3AEIF4HAPOBEC3G
Hydrochloric Acid SCHEMBL4755068 0.82 NOTUM (0.56) NOTUMPABPC1APOBEC3AEIF4HAPOBEC3G
SCHEMBL13900784 0.82 NOTUM (0.61) NOTUMAPPGRM5MAPTLMNA
SCHEMBL12216504 0.80 MAPT (0.52) NOTUMPABPC1APOBEC3AEIF4HAPOBEC3G
Hydrochloric Acid SCHEMBL11601600 0.79 CYP11B2 (0.43) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
Hydrochloric Acid SCHEMBL11503645 0.78 CYP11B2 (0.42) PABPC1APOBEC3AEIF4HAPOBEC3GMAPT
SCHEMBL9610050 0.78 APP (0.55) NOTUMAPPGRM5MAPTLMNA
SCHEMBL17224548 0.75 APP (0.63) NOTUMAPPGRM5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240069257-A1 CHOLESTERIC LIQUID CRYSTAL LAYER, METHOD OF FORMING CHOLESTERIC LIQUID CRYSTAL LAYER, LAMINATE, LIGHT GUIDE ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2024-02-29 — — US disclosed
US-11828960-B2 Cholesteric liquid crystal layer, method of forming cholesteric liquid crystal layer, laminate, light guide element, and image display device FUJIFILM CORPORATION (JP) 2023-11-28 — — US disclosed
US-8153246-B2 Optical compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-04-10 — — US disclosed
US-7658864-B2 Liquid crystal composition, optical compensation film and liquid crystal display device FUJIFILM CORPORATION (JP) 2010-02-09 — — US disclosed
US-20090273740-A1 OPTICAL COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-11-05 — — US disclosed
US-20090009693-A1 Liquid Crystal Composition, Optical Compensation Film and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-01-08 — — US disclosed
US-7311950-B2 Composition, optical compensatory film and liquid crystal display FUJIFILM CORPORATION (JP) 2007-12-25 — — US disclosed
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