Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928719 | 0.95 | NOTUM (0.61) | APPNOTUMGRM5CYP1A1CYP1A2 | |
| SCHEMBL13900784 | 0.95 | NOTUM (0.61) | APPNOTUMGRM5CYP1A1CYP1A2 | |
| SCHEMBL17224548 | 0.93 | APP (0.63) | APPNOTUMGRM5MAPTFFAR1 | |
| SCHEMBL2925968 | 0.91 | APP (0.67) | APPNOTUMGRM5CYP1A2MAPT | |
| SCHEMBL9610040 | 0.91 | MAPT (0.53) | APPNOTUMGRM5CYP1A1CYP1A2 | |
| SCHEMBL13219274 | 0.88 | MAPT (0.58) | NOTUMGRM5CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL30718530 | 0.85 | MAPT (0.61) | APPNOTUMGRM5CYP1A1CYP1A2 | |
| SCHEMBL5949303 | 0.85 | APP (0.75) | APPGRM5CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL7261719 | 0.84 | MAPT (0.46) | NOTUMGRM5CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4324850 | 0.84 | ASIC3 (0.53) | APPNOTUMGRM5KCNH2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135249-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-31 | — | — | US | disclosed |
| US-20110024691-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135249-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | AHR, TYR, ARNT | APP 1595/4885NOTUM 4721/4885GRM5 4146/4885 |
| US-20110024691-A1 | AROMATIC AND AROMATIC/HETEROAROMATIC MOLECULAR STRUCTURES WITH CONTROLLABLE ELECTRON CONDUCTING PROPERTIES | AHR, TYR, ARNT | APP 1595/4885NOTUM 4721/4885GRM5 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.