Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GRM5 | P41594 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9610050 | 0.95 | APP (0.55) | NOTUMAPPGRM5MAPTCYP1A1 | |
| SCHEMBL9928719 | 0.91 | NOTUM (0.61) | NOTUMAPPGRM5MAPTCYP1A1 | |
| SCHEMBL30718530 | 0.91 | MAPT (0.61) | NOTUMAPPGRM5MAPTCYP1A1 | |
| SCHEMBL13219274 | 0.88 | MAPT (0.58) | NOTUMGRM5MAPTCYP1A1CYP1A2 | |
| SCHEMBL17224548 | 0.88 | APP (0.63) | NOTUMAPPGRM5MAPT | |
| SCHEMBL9610040 | 0.85 | MAPT (0.53) | NOTUMAPPGRM5MAPTCYP1A1 | |
| SCHEMBL2925968 | 0.85 | APP (0.67) | NOTUMAPPGRM5MAPTCYP1A2 | |
| SCHEMBL5949303 | 0.85 | APP (0.75) | APPGRM5MAPTCYP1A1CYP1A2 | |
| SCHEMBL5886608 | 0.83 | APP (0.71) | APPGRM5MAPTCYP1A1CYP1A2 | |
| SCHEMBL1108052 | 0.82 | NOTUM (0.45) | NOTUMAPPGRM5MAPTCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7504505-B2 | Synthetic nanopores for DNA sequencing | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2009-03-17 | — | — | US | disclosed |