Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071655 | 0.83 | SLC6A4 (0.53) | POLBOPRM1OPRL1SLC6A4SLC6A3 | |
| SCHEMBL11078301 | 0.82 | OPRL1 (0.58) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11066830 | 0.81 | OPRL1 (0.46) | OPRM1OPRL1GRIN2BSLC18A3 | |
| Ethylbenzene SCHEMBL11080651 | 0.78 | OPRL1 (0.45) | OPRM1OPRL1SLC6A4SLC6A3 | |
| SCHEMBL11065445 | 0.77 | OPRM1 (0.58) | OPRM1OPRL1GRIN2BSLC18A3 | |
| SCHEMBL11073158 | 0.77 | OPRM1 (0.50) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11079938 | 0.76 | OPRL1 (0.46) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11070020 | 0.75 | OPRM1 (0.49) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11077368 | 0.75 | GRIN2B (0.42) | OPRM1OPRL1GRIN2BSLC18A3 | |
| SCHEMBL11076128 | 0.74 | CHIA (0.44) | OPRM1OPRL1GRIN2BSLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |