Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL11080817 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2PTBP1MAPTKMT2A | |
| SCHEMBL11081196 | 0.82 | POLB (0.52) | LMNAKMT2ANPC1MEN1GAA | |
| SCHEMBL11085958 | 0.75 | CYP3A4 (0.54) | LMNASMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL11082071 | 0.74 | MAPT (0.58) | SMN1; SMN2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL11077482 | 0.74 | CYP3A4 (0.53) | LMNASMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL11083167 | 0.73 | RXFP1 (0.53) | SMN1; SMN2MAPTRXFP1KDR | |
| SCHEMBL11086777 | 0.71 | MEN1 (0.60) | LMNASMN1; SMN2MAPTKMT2ANPC1 | |
| Ethyl Chloride SCHEMBL29266256 | 0.70 | KDM4E (0.41) | SMN1; SMN2MAPTKMT2ANPC1RAB9A | |
| SCHEMBL10352599 | 0.69 | ALDH1A1 (0.54) | LMNASMN1; SMN2MAPTKMT2ANPC1 | |
| SCHEMBL11075368 | 0.69 | MAPT (0.49) | LMNASMN1; SMN2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450167-A | TRANQUILIZERS; PSYCHOLOGICAL DISORDERS | ROUSSEL UCLAF (FR) | 1984-05-22 | — | — | US | disclosed |