Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | CPA1 | P15085 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555564 | 0.85 | GABBR2 (0.47) | GSRKMT2AMEN1CYP1A2TSHR | |
| SCHEMBL27836708 | 0.84 | GABBR2 (0.46) | GSRKMT2AMEN1CYP1A2TSHR | |
| SCHEMBL1305450 | 0.82 | CYP2C19 (0.46) | GSRCYP1A2GABBR2GABBR1CPA1 | |
| SCHEMBL28123480 | 0.82 | KMT2A (0.51) | GSRKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL27604686 | 0.81 | GSR (0.41) | GSRKMT2AMEN1CYP1A2TSHR | |
| SCHEMBL1304856 | 0.78 | ATM (0.51) | KMT2AMEN1CYP1A2CYP2D6CYP3A4 | |
| SCHEMBL5682429 | 0.78 | ALDH1A1 (0.43) | GSRKMT2AMEN1CYP1A2FBP1 | |
| SCHEMBL366294 | 0.78 | FAAH (0.43) | GSRKMT2AMEN1CYP1A2CYP2D6 | |
| SCHEMBL3336779 | 0.77 | GSR (0.55) | GSRKMT2AMEN1CPA1CYP2D6 | |
| SCHEMBL27340252 | 0.77 | GSR (0.42) | GSRKMT2AMEN1TSHRFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4408057-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-10-04 | — | — | US | disclosed |
| US-4368205-A | 4-Heterocyclic-substituted-2-indanyl alcohols and insecticidal ester derivatives | FMC CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |