Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | GSR | P00390 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28123480 | 0.81 | KMT2A (0.51) | GSRKMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL2555564 | 0.81 | GABBR2 (0.47) | GSRKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL368261 | 0.80 | FAAH (0.40) | FAAHGSRKMT2APTGS2ALDH1A1 | |
| SCHEMBL27836708 | 0.80 | GABBR2 (0.46) | GSRKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL1305450 | 0.78 | CYP2C19 (0.46) | GSRALDH1A1MAPTNPSR1KDM4E | |
| SCHEMBL11081089 | 0.78 | GSR (0.41) | GSRKMT2AMAPTMEN1CYP1A2 | |
| SCHEMBL1304856 | 0.77 | ATM (0.51) | KMT2AALDH1A1MAPTNPSR1MEN1 | |
| SCHEMBL27332943 | 0.77 | PTGS2 (0.47) | FAAHPTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL6261926 | 0.75 | GSR (0.41) | GSRKMT2AALDH1A1MAPTNPSR1 | |
| SCHEMBL27604686 | 0.74 | GSR (0.41) | GSRKMT2AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009372-A2 | TRIAZOLIUM CARBENE CATALYSTS AND PROCESSES FOR ASYMMETRIC CARBON-CARBON BOND FORMATION | COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-01-19 | — | — | WO | claimed |