Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089788 | 0.82 | MAPT (0.51) | KMT2AMEN1KDM4ETDP1MAPT | |
| SCHEMBL11079756 | 0.75 | KMT2A (0.47) | KMT2APOLBALDH1A1CYP3A4TDP1 | |
| SCHEMBL9871055 | 0.74 | ACHE (0.57) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL11082068 | 0.72 | KMT2A (0.43) | KMT2AMEN1ALDH1A1KDM4EMAPT | |
| SCHEMBL7831869 | 0.69 | MEN1 (0.49) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL20804319 | 0.68 | ALDH1A1 (0.58) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL10341837 | 0.68 | KMT2A (0.65) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL3154100 | 0.68 | POLB (0.67) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL11285216 | 0.67 | SMN1; SMN2 (0.49) | KMT2APOLBMEN1ALDH1A1KDM4E | |
| SCHEMBL1731815 | 0.67 | POLB (0.50) | KMT2APOLBMEN1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |