Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081247 | 0.85 | KMT2A (0.44) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL11082068 | 0.83 | KMT2A (0.43) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL11085801 | 0.83 | DDB1 (0.51) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL11080183 | 0.83 | MEN1 (0.57) | SMN1; SMN2GAAMAPTKMT2AMEN1 | |
| SCHEMBL11079280 | 0.81 | KMT2A (0.51) | SMN1; SMN2MAPTTP53LMNAKMT2A | |
| SCHEMBL11079756 | 0.80 | KMT2A (0.47) | SMN1; SMN2MAPTTP53LMNAKMT2A | |
| SCHEMBL11084167 | 0.80 | USP2 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11089788 | 0.75 | MAPT (0.51) | SMN1; SMN2GAAMAPTKMT2AMEN1 | |
| SCHEMBL11395312 | 0.72 | RAB9A (0.44) | SMN1; SMN2GAAMAPTLMNAKMT2A | |
| SCHEMBL11285216 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2GAAMAPTTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |