Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081247 | 0.81 | KMT2A (0.44) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11075283 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL11082068 | 0.80 | KMT2A (0.43) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11079756 | 0.76 | KMT2A (0.47) | TSHRCYP2D6SMN1; SMN2CYP1A2KMT2A | |
| SCHEMBL20189376 | 0.75 | USP2 (0.46) | USP2CYP19A1HTR2CTSHRCYP2D6 | |
| SCHEMBL11085436 | 0.74 | CYP19A1 (0.41) | CYP19A1TSHRSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL11089788 | 0.72 | MAPT (0.51) | HTR2CSMN1; SMN2CYP1A2MEN1CYP2C9 | |
| SCHEMBL7267266 | 0.69 | GSK3A (0.63) | USP2CYP19A1HTR2CSMN1; SMN2MEN1 | |
| SCHEMBL11079280 | 0.69 | KMT2A (0.51) | SMN1; SMN2CYP1A2MEN1KMT2ACYP3A4 | |
| SCHEMBL8136911 | 0.68 | POLB (0.65) | USP2CYP19A1HTR2CTSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426522-A | ANTICOCCIDIAL | ABIC LTD. (IL) | 1984-01-17 | — | — | US | disclosed |
| EP-0058534-A2 | Hexahydro-1,2,4-triazine-3,5-dione derivatives and their use as feed additives | ABIC LTD. (IL) | 1982-08-25 | — | — | EP | disclosed |