Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 4/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166732 | 0.73 | L3MBTL1 (0.39) | S1PR5S1PR1POLBL3MBTL1NPC1 | |
| SCHEMBL16166734 | 0.69 | POLB (0.45) | S1PR5S1PR1POLBL3MBTL1ALDH1A1 | |
| SCHEMBL11082188 | 0.69 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL11082183 | 0.69 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL7814243 | 0.69 | POLB (0.54) | S1PR5S1PR1POLBL3MBTL1NPC1 | |
| SCHEMBL16398595 | 0.68 | POLB (0.40) | S1PR5S1PR1POLBALDH1A1CNR2 | |
| Phenethylamine SCHEMBL7418787 | 0.67 | HTR2A (0.59) | S1PR5S1PR1POLBL3MBTL1NPC1 | |
| SCHEMBL6819745 | 0.66 | TRPA1 (0.47) | S1PR1SMN1; SMN2 | |
| SCHEMBL14379104 | 0.65 | OPRL1 (0.46) | POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL1439425 | 0.65 | S1PR5 (0.48) | S1PR5S1PR1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457924-A | PENICILLINS, OXAPENICILLINS, BETA-LACTAMASE INHIBITORS | PFIZER, INC. (US) | 1984-07-03 | — | — | US | disclosed |