Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | TMPRSS4 | Q9NRS4 | 7/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462798 | 0.86 | RAB9A (0.50) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL427243 | 0.86 | SMN1; SMN2 (0.59) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL927354 | 0.85 | TMPRSS4 (0.50) | RAB9ACYP1A2CYP2D6CYP2C19TP53 | |
| SCHEMBL7779187 | 0.83 | RAB9A (0.50) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL31591114 | 0.83 | RAB9A (0.50) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL3922426 | 0.83 | RAB9A (0.47) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL2634026 | 0.82 | KDM4E (0.62) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL28661823 | 0.82 | AR (0.55) | RAB9ACYP1A2CYP2D6CYP2C19CES2 | |
| Hydrochloric Acid SCHEMBL4377513 | 0.81 | RAB9A (0.46) | RAB9ACYP1A2CYP2D6CYP2C19SMN1; SMN2 | |
| SCHEMBL25387702 | 0.81 | CES2 (0.47) | CES2FLT1FLT4KDRTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551560-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | Huyabio International, LLC (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-118255659-A | Preparation method of 2-trifluoromethyl benzoyl chloride and derivatives thereof | 辽宁天予化工有限公司 | 2024-06-28 | — | — | CN | disclosed |
| WO-2023177591-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | HUYABIO INTERNATIONAL, LLC (US) | 2023-09-21 | — | — | WO | disclosed |
| US-20230286948-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | HUYABIO INTERNATIONAL, LLC | 2023-09-14 | — | — | US | disclosed |
| US-20230286948-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | HUYABIO INTERNATIONAL, LLC | 2023-09-14 | — | — | US | disclosed |
| US-20230286948-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | HUYABIO INTERNATIONAL, LLC | 2023-09-14 | — | — | US | disclosed |
| CN-111348996-B | 2-benzoyl malonate compound, and preparation method and application thereof | 江苏联化科技有限公司 | 2023-09-08 | — | — | CN | disclosed |
| CN-116535358-A | Benzamide derivative with sulfur-containing cyano pyrazole structure, preparation method and application thereof | 西北农林科技大学 | 2023-08-04 | — | — | CN | disclosed |
| CN-113968775-A | Intermediate compound for preparing 4-chloro-2-trifluoromethyl-acetophenone, preparation method and application thereof | 江苏丰山集团股份有限公司 | 2022-01-25 | — | — | CN | disclosed |
| WO-2020132792-A1 | 2-BENZOYL MALONATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏联化科技有限公司 | 2020-07-02 | — | — | WO | disclosed |
| CN-1066439-C | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGROCHIMIE (GB) | 2001-05-30 | — | — | CN | disclosed |
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| CN-1037058-C | Herbicide composition and use thereof | RHONE POULENC AGRICULTURE (GB) | 1998-01-21 | — | — | CN | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| CN-1141294-A | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| EP-0418175-B1 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1996-07-17 | — | — | EP | disclosed |
| CN-1050188-A | ISOXAZOLES HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1991-03-27 | — | — | CN | disclosed |
| EP-0418175-A2 | Isoxazoles herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1991-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230286948-A1 | HALOALKYLPYRIDYL TRIAZOLE MLL1-WDR5 PROTEIN-PROTEIN INTERACTION INHIBITOR | WDR5, WDR1, WDR3 | RAB9A 3700/4885CYP1A2 4067/4885CYP2D6 4055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.