Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28462798 | 0.88 | RAB9A (0.50) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL110827 | 0.86 | RAB9A (0.49) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL950905 | 0.86 | ALDH1A1 (0.57) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL38420096 | 0.86 | ALDH1A1 (0.57) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL7779187 | 0.85 | RAB9A (0.50) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL31591114 | 0.85 | RAB9A (0.50) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| SCHEMBL3922426 | 0.85 | RAB9A (0.47) | SMN1; SMN2TSHRCASP1GRIK1TP53 | |
| Hydrochloric Acid SCHEMBL4377513 | 0.83 | RAB9A (0.46) | SMN1; SMN2GRIK1TP53ALDH1A1RAB9A | |
| SCHEMBL26023312 | 0.82 | RAB9A (0.48) | SMN1; SMN2GRIK1TP53RAB9ACYP1A2 | |
| SCHEMBL12132735 | 0.82 | ALDH1A1 (0.61) | SMN1; SMN2GRIK1TP53ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551633-B1 | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | LEO PHARMA AS (DK) | 2021-03-31 | — | — | EP | claimed |
| CN-110088108-A | SUBSTITUTED PYRAZOLOAZEPIN-4-ONES AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | 利奥制药有限公司 | 2019-08-02 | — | — | CN | claimed |
| EP-3802500-B1 | MELANOCORTIN SUBTYPE-2 RECEPTOR (MC2R) ANTAGONISTS AND USES THEREOF | CRINETICS PHARMACEUTICALS INC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4714953-A1 | MELANOCORTIN 2-TYPE RECEPTOR ANTAGONIST | Scohia Pharma, Inc. (JP) | 2026-03-25 | — | — | EP | disclosed |
| US-12479828-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12479825-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12410170-B2 | 2,3,5-trisubstituted pyrazolo[1,5-A]pyrimidine compounds | ARCUS BIOSCIENCES, INC. (US) | 2025-09-09 | — | — | US | disclosed |
| EP-4605364-A1 | PROCESS FOR THE PREPARATION OF 4-CHLORO-2-(TRIFLUOROMETHYL)PHENYL GRIGNARD COMPOUND AND DERIVATIVES THEREOF | BASF Agro B.V. (NL) | 2025-08-27 | — | — | EP | disclosed |
| CN-120051451-A | Process for preparing 4-chloro-2- (trifluoromethyl) phenyl grignard compounds and derivatives thereof | 巴斯夫农业公司 | 2025-05-27 | — | — | CN | disclosed |
| US-20250011326-A1 | FUSED HETEROCYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF HBV INFECTION | Janssen Sciences Ireland Unlimited Company (IE) | 2025-01-09 | — | — | US | disclosed |
| WO-2024237266-A1 | MELANOCORTIN 2-TYPE RECEPTOR ANTAGONIST | 株式会社スコヒアファーマ | 2024-11-21 | — | — | WO | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0487357-B1 | 4 Benzoyl isoxazole derivatives | RHONE POULENC AGRICULTURE (GB) | 1997-07-02 | — | — | EP | disclosed |
| CN-1061596-A | 4-Benzoylisoxazole Derivatives | RHONE POULENC AGRICULTURE (GB) | 1992-06-03 | — | — | CN | disclosed |
| EP-0487357-A1 | 4 Benzoyl isoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1992-05-27 | — | — | EP | disclosed |
| EP-0097357-B1 | PROCESS FOR PREPARING TRIFLUOROMETHYLBENZENE DERIVATIVES | Daikin Kogyo Co., Ltd. (JP) | 1986-01-08 | — | — | EP | disclosed |
| US-4493800-A | REACTING A TRIFLUOROMETHYLHALOGENOBENZENE WITH COPPER CYANIDE | DAIKIN KOGYO CO., LTD. (JP) | 1985-01-15 | — | — | US | disclosed |
| EP-0097357-A1 | Process for preparing trifluoromethylbenzene derivatives | Daikin Kogyo Co., Ltd. (JP) | 1984-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410170-B2 | 2,3,5-trisubstituted pyrazolo[1,5-A]pyrimidine compounds | PIK3CA, PIK3CG, PIK3CD | SMN1; SMN2 3842/4885TSHR 3567/4885CASP1 682/4885 |
| US-12479825-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | SMN1; SMN2 2938/4885TSHR 102/4885CASP1 4853/4885 |
| US-20250011326-A1 | FUSED HETEROCYCLIC DERIVATIVES AND THEIR USE IN THE TREATMENT OF HBV INFECTION | HAVCR2, HCCS, HDGF | SMN1; SMN2 4515/4885TSHR 3425/4885CASP1 1799/4885 |
| US-12479828-B2 | Melanocortin subtype-2 receptor (MC2R) antagonists and uses thereof | MC3R, MC1R, MC2R | SMN1; SMN2 2938/4885TSHR 102/4885CASP1 4853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.